Electronic pill, the first real fart detector

In combination with the receiver and the mobile app, the capsule moves from the stomach to the colon, during which time gas-related data is sent back. Previously, the researchers tested a similar capsule on pigs and expanded the project to humans.

A research team in Australia is working on an unprecedented innovation – the first true fart detector.

They recently announced an electronic pill designed to monitor gas levels in the human digestive system. In combination with the receiver and the mobile app, the capsule moves from the stomach to the colon, during which time gas-related data is sent back. Previously, the researchers tested a similar capsule on pigs and expanded the project to humans.

The pill has a length of 26 mm and an outer diameter of 9.8 mm, which is as large as many capsules on the market. It is packaged in a polymer housing to control temperature, integrates sensors containing CO2, H2 and O2, and has a silver oxide Battery and transmission system. At one end, the capsule is breathable to rapidly diffuse the gas in the intestine.

In the journal Nature Electronics, Kourosh Kalantar-Zadeh of the Royal Melbourne Institute of Technology (RMIT) and Peter Gibson of Monash University describe their desire to understand the complex workings of the human gut, including the specifics of each part of the intestine. Conditions, the role of microorganisms, and even the effects of certain foods on the intestines.

"We found that the stomach releases oxidized chemicals to break down and beat foreign compounds that stay in the stomach," Kalantar-Zadeh said. In the past, people did not know how the intestine responded to foreign bodies.

These studies have been difficult before taking pills because of the need for invasive procedures. Researchers in the journal article pointed out that they are building a commercial company that can develop and test pilot projects outside the capsule.

Electronic pill, the first real fart detector

In the trial, the capsule was tested on 6 healthy volunteers and monitored by ultrasound.

It took 20 hours for the pill to pass through the body, which lasted 4.5 hours in the stomach, 2.5 hours in the small intestine, and finally passed through the colon for 13 hours, measuring the gas throughout the body. Researchers can identify the process of the gut by observing the rise and fall in the number of CO2, H2, and O2 and compare it to our current understanding of gut bacteria.

The research team asked a volunteer to swallow two pills - one for a high-fiber diet (50 grams a day) for two days and the other for a two-day low-fiber diet (15 grams per day). When eating high fiber, the pill stayed in his body for 23 hours, but he experienced abdominal pain. The pill experiment showed that when the intestinal tract is unhealthy, the bacterial value of oxygen and feces will increase.

In the case of a low-fiber diet, it takes more than three days for the pill to reappear on a daily basis. It will stay in the stomach for 13 hours, stay in the small intestine for 5.5 hours, stay in the colon for 54 hours, and finally ask the volunteer to take a high dose. The fiber can be discharged. Before taking high fiber, the value of H2 dropped sharply and rose again after 12 hours.

The remaining volunteers either had a high-fiber diet (no high volunteers above) or a low-fiber diet. The results are similar.

Researchers believe that this technology will help people have a more comprehensive understanding of the health of the intestines and intestines, and ultimately achieve better medical care. Although swallowing a sensor-filled pill may make some patients feel uncomfortable, it is undoubtedly a less risky alternative and may soon become a regular part of medical evaluation.

“Although the data is limited to a small range, it is encouraging that smart, swallowable capsules can provide new insights into gastrointestinal motility.” Brigham's gastroenterologist, biomedical engineer Giovanni Traverso pointed out, “This really expands the range of applications for ingestible sensors.”

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